Bronchial hyperreactivity, increased endotoxin lethality and melanocytic tumorigenesis in transgenic mice overexpressing platelet-activating factor receptor.

Although platelet-activating factor (PAF) has been shown to exert pleiotropic effects on isolated cells or tissues, controversy still exists as to whether it plays significant pathophysiological roles in vivo. To answer this question, we established transgenic mice over-expressing a guinea-pig PAF r...

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Detalhes bibliográficos
Main Authors: Ishii, S, Nagase, T, Tashiro, F, Ikuta, K, Sato, S, Waga, I, Kume, K, Miyazaki, J, Shimizu, T
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169620/
https://ncbi.nlm.nih.gov/pubmed/9009274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.1.133
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