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Involvement of Nuclear Export in Human Papillomavirus Type 18 E6-Mediated Ubiquitination and Degradation of p53

The E6 protein from high-risk human papillomaviruses (HPVs) targets the p53 tumor suppressor for degradation by the proteasome pathway. This ability contributes to the oncogenic potential of these viruses. However, several aspects concerning the mechanism of E6-mediated p53 degradation at the cellul...

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Bibliografske podrobnosti
Main Authors: Stewart, Deborah, Ghosh, Anirban, Matlashewski, Greg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168768/
https://ncbi.nlm.nih.gov/pubmed/15994771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8773-8783.2005
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