Evaluating the Immunogenicity of a Disulfide-Stabilized, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1

The human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) complex comprises three gp120 exterior glycoproteins each noncovalently linked to a gp41 transmembrane glycoprotein. Monomeric gp120 proteins can elicit antibodies capable of neutralizing atypically sensitive test viruses in...

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Bibliographische Detailangaben
Hauptverfasser: Beddows, Simon, Schülke, Norbert, Kirschner, Marc, Barnes, Kelly, Franti, Michael, Michael, Elizabeth, Ketas, Thomas, Sanders, Rogier W., Maddon, Paul J., Olson, William C., Moore, John P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168742/
https://ncbi.nlm.nih.gov/pubmed/15994775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8812-8827.2005
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