Drug-Induced Regulation of the MDR1 Promoter in Candida albicans

Resistance of Candida albicans to azole antifungal drugs is mediated by two types of efflux pumps, encoded by the MDR1 gene and the CDR gene family. MDR1 mRNA levels in a susceptible clinical isolate are induced by benomyl (BEN) but not by other drugs previously shown to induce MDR1. To monitor MDR1...

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Detalhes bibliográficos
Main Authors: Harry, Jo Beth, Oliver, Brian G., Song, Jia L., Silver, Peter M., Little, John T., Choiniere, Jake, White, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168718/
https://ncbi.nlm.nih.gov/pubmed/15980350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2785-2792.2005
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