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Antimicrobial Activity of Novel Dendrimeric Peptides Obtained by Phage Display Selection and Rational Modification

A large 10-mer phage peptide library was panned against whole Escherichia coli cells, and an antimicrobial peptide (QEKIRVRLSA) was selected. The peptide was synthesized in monomeric and dendrimeric tetrabranched form (multiple antigen peptide [MAP]), which generally allows a dramatic increase of pe...

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Detalhes bibliográficos
Main Authors: Pini, Alessandro, Giuliani, Andrea, Falciani, Chiara, Runci, Ylenia, Ricci, Claudia, Lelli, Barbara, Malossi, Monica, Neri, Paolo, Rossolini, Gian Maria, Bracci, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168694/
https://ncbi.nlm.nih.gov/pubmed/15980334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2665-2672.2005
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