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Efficacy of the Antiadhesin Octyl O-(2-Acetamido-2-Deoxy-β-d- Galactopyranosyl)-(1-4)-2-O-Propyl-β-d-Galactopyranoside (Fimbrigal-P) in a Rat Oral Candidiasis Model

Adherence of Candida albicans to buccal epithelial cells via its fimbrial subunit requires the minimal disaccharide sequence β-GalNAc(1-4)-β-galactosidase in host cell receptors asialo-GM1 or asialo-GM2. This and other disaccharides and some of its synthetic derivatives have been shown to inhibit pu...

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Detalhes bibliográficos
Main Authors: Foldvari, M., Jaafari, M. R., Radhi, J., Segal, D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168655/
https://ncbi.nlm.nih.gov/pubmed/15980365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2887-2894.2005
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