Antagonizing Deactivating Cytokines To Enhance Host Defense and Chemotherapy in Experimental Visceral Leishmaniasis

In experimental visceral leishmaniasis, inhibition of interleukin 10 (IL-10) signaling enhances Th1-cell-associated responses, promoting gamma interferon (IFN-γ) secretion, granuloma assembly, macrophage activation with substantial liver parasite killing, and synergy with pentavalent antimony (Sb) c...

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Detalhes bibliográficos
Main Authors: Murray, Henry W., Flanders, Kathleen C., Donaldson, Debra D., Sypek, Joseph P., Gotwals, Philip J., Liu, Jianguo, Ma, Xiaojing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168607/
https://ncbi.nlm.nih.gov/pubmed/15972476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.3903-3911.2005
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