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Saturation of Immunoglobulin E (IgE) Binding Sites by Polyclonal IgE Does Not Explain the Protective Effect of Helminth Infections against Atopy

One hypothesis for the decreased rates of atopy observed among helminth-infected individuals is that parasite-induced polyclonal immunoglobulin E (IgE) outcompetes allergen-specific IgE for FcɛRI binding on basophils and mast cells. In experiments with fresh blood drawn from filaria-infected patient...

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Detalhes bibliográficos
Main Authors: Mitre, Edward, Norwood, Stephanie, Nutman, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168579/
https://ncbi.nlm.nih.gov/pubmed/15972499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4106-4111.2005
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