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Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide–adenine dinucleotide

The effects on the pancreatic B cell of streptozotocin and its aglucone derivative N-nitrosomethylurea were investigated in obese–hyperglycaemic mice and their lean littermates. Both streptozotocin and N-nitrosomethylurea were found to be B-cytotoxic although N-nitrosomethylurea produced less islet...

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Detalles Bibliográficos
Main Authors: Gunnarsson, Rolf, Berne, Christian, Hellerström, Claes
Formato: Artigo
Idioma:Inglês
Publicado: 1974
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168026/
https://ncbi.nlm.nih.gov/pubmed/4374939
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