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Sterol structural requirements for inhibition of streptolysin O activity

Reduced streptolysin O, a toxin produced by certain β-haemolytic streptococci, lyses human erythrocytes. The reaction is inhibited by cholesterol at concentrations of about 1.0μg/ml. Other sterols inhibit the lysin and there is a specific requirement for a 3β-hydroxyl group. Inhibition was obtained...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Watson, Kenneth C., Kerr, Eric J. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1974
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167975/
https://ncbi.nlm.nih.gov/pubmed/4451554
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