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Illegitimate recombination occurs between the replication origin of the plasmid pC194 and a progressing replication fork.

Hybrids between plasmids pC194, pBR322 and the bacteriophage f1 undergo deletions in Escherichia coli. The deletions end most often between nucleotides 1445 and 1446 of pC194. That site probably corresponds to a nick in the replication origin of this plasmid. The localization of the other deletion e...

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Main Authors: Michel, B, Ehrlich, S D
格式: Artigo
語言:Inglês
出版: 1986
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167412/
https://ncbi.nlm.nih.gov/pubmed/3030736
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