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A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

We describe the structure and transcriptional activity of the 5' portion of the alpha-cardiac actin gene of BALB/c mice. Southern blotting and DNA sequencing reveal that the promoter and first three exons of the gene are present as perfect repeats in a direct duplication of 9.5 kbp situated imm...

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Bibliographic Details
Main Authors: Garner, I, Minty, A J, Alonso, S, Barton, P J, Buckingham, M E
Format: Artigo
Language:Inglês
Published: 1986
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167153/
https://ncbi.nlm.nih.gov/pubmed/3023046
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