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Stable gene transfer and tissue-specific expression of a human globin gene using adenoviral vectors.

Helper-free double recombinant adenoviruses containing a genomic human globin gene and the neomycin resistance gene (neoR) have been constructed. The inserted globin and neoR genes are stable and transcription of two human globin genes (beta and a hybrid gamma-beta gene) is correctly initiated at th...

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Autori principali: Karlsson, S, Van Doren, K, Schweiger, S G, Nienhuis, A W, Gluzman, Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1986
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1167123/
https://ncbi.nlm.nih.gov/pubmed/3780679
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