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DNA gyrase complex with DNA: determinants for site-specific DNA breakage.

DNA gyrase catalyses DNA supercoiling by making a transient double-stranded DNA break within its 120-150 bp binding site on DNA. Addition of the inhibitor oxolinic acid to the reaction followed by detergent traps a covalent enzyme-DNA intermediate inducing sequence-specific DNA cleavage and revealin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fisher, L M, Barot, H A, Cullen, M E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1986
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166956/
https://ncbi.nlm.nih.gov/pubmed/3015604
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