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Collecting duct-specific deletion of peroxisome proliferator-activated receptor γ blocks thiazolidinedione-induced fluid retention

The peroxisome proliferator-activated receptor subtype γ (PPARγ) ligands, namely the synthetic insulin-sensitizing thiazolidinedione (TZD) compounds, have demonstrated great potential in the treatment of type II diabetes. However, their clinical applicability is limited by a common and serious side...

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Autori principali: Zhang, Hui, Zhang, Aihua, Kohan, Donald E., Nelson, Raoul D., Gonzalez, Frank J., Yang, Tianxin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166599/
https://ncbi.nlm.nih.gov/pubmed/15956187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501744102
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