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Histidine residues and the enzyme activity of pig heart supernatant malate dehydrogenase (Short Communication)

1. Supernatant pig heart malate dehydrogenase is completely inhibited by reaction with diethyl pyrocarbonate at pH6.5, when 0.58±0.1 residue of ethoxycarbonylhistidine is formed per NADH-binding site. 2. Oxaloacetate and hydroxymalonate protect the enzyme from inhibition in the absence of coenzyme....

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Detalhes bibliográficos
Main Authors: Holbrook, J. John, Lodola, A., Illsley, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166348/
https://ncbi.nlm.nih.gov/pubmed/4368772
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