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Effects of collagen and of aspirin on the concentration of guanosine 3′:5′-cyclic monophosphate in human blood platelets: measurement by a prelabelling technique (Short Communication)

A method is described for isolating cyclic [(3)H]GMP from platelets preincubated with [(3)H]guanine. Collagen increased and aspirin decreased the cyclic [(3)H]GMP concentration in platelets. The results are consistent with a role for cyclic GMP in the platelet release reaction.

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Detalhes bibliográficos
Main Authors: Haslam, R. J., McClenaghan, M. D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166211/
https://ncbi.nlm.nih.gov/pubmed/4362746
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