The reaction of diethyl pyrocarbonate with pyruvate kinase (Short Communication)

Diethyl pyrocarbonate inactivates muscle pyruvate kinase with the substitution of 3–4 histidine residues per subunit. Phosphoenolpyruvate, ATP and ADP to a lesser extent, and Mg(2+) and pyruvate to a small extent, protect against inactivation.

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Bibliografiske detaljer
Main Authors: Dann, Leighton G., Britton, Hubert G.
Format: Artigo
Sprog:Inglês
Udgivet: 1974
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166129/
https://ncbi.nlm.nih.gov/pubmed/4824216
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