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The reaction of alkylating agents with bacteriophage R17. Biological effects of phosphotriester formation

The extent of biological inactivation and of the degradation of the RNA after reaction of bacteriophage R17 with ethyl methanesulphonate, isopropyl methanesulphonate and N-ethyl-N-nitrosourea was studied. Formation of breaks in the RNA chain probably results from hydrolysis of phosphotriesters forme...

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Библиографические подробности
Главные авторы: Shooter, Kenneth V., Howse, Ruth, Merrifield, R. Kenneth
Формат: Artigo
Язык:Inglês
Опубликовано: 1974
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166119/
https://ncbi.nlm.nih.gov/pubmed/4363112
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