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Inhibition by ricin of protein synthesis in vitro: 60S ribosomal subunit as the target of the toxin (Short Communication)

Poly(U)-directed polyphenylalanine synthesis by rat liver ribosomes is strongly inhibited by ricin. Experiments involving hybridization between subunits derived from normal and ricin-treated ribosomes demonstrate that the 60S subunit is the site of action of the toxin. The toxin inactivates the 60S...

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Detalhes bibliográficos
Main Authors: Sperti, Simonetta, Montanaro, Lucio, Mattioli, Alessandro, Stirpe, Fiorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166019/
https://ncbi.nlm.nih.gov/pubmed/4360718
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