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Mechanism of action of a microsomal inhibitor of protein synthesis potentiated by oxidized glutathione

Extracts of microsomal fractions cause an inhibition of protein synthesis that is most pronounced in the presence of 0.1mm-GSSG and 0.01mm-GTP, and is abolished by thiol or 0.4mm-GTP (Scornik et al., 1967). Fractionation of microsomal extracts showed that this inhibition of protein synthesis was cau...

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Autori principali: Rupniak, H. T. R., Quincey, R. V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1973
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165959/
https://ncbi.nlm.nih.gov/pubmed/4359517
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