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The effect of trimethoprim on macromolecular synthesis in Escherichia coli. Regulation of ribonucleic acid synthesis by `magic spot' nucleotides
During the inhibition of RC(str), but not RC(rel) mutants of Escherichia coli by trimethoprim the unusual nucleotides MSI (guanosine tetraphosphate, ppGpp) and MSII rapidly accumulated. The production of these nucleotides was not dependent on the addition of nucleotide base supplements to RC(str) cu...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1973
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1165950/ https://ncbi.nlm.nih.gov/pubmed/4590200 |
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