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Effect of Intrastrain Variation in the Amount of Capsular Polysaccharide on Genetic Transformation of Streptococcus pneumoniae: Implications for Virulence Studies of Encapsulated Strains

The degrees of competence of opaque and transparent colony variants of Streptococcus pneumoniae were compared. The transparent variants were transformed at 9- to 670-fold-higher rates than the opaque variants, independent of the DNA incorporated, due to decreased expression of capsular polysaccharid...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Weiser, Jeffrey N., Kapoor, Miki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116567/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3690-3692.1999
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