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Synthesis of thiol-containing analogues of puromycin and a study of their interaction with N-acetylphenylalanyl-transfer ribonucleic acid on ribosomes to form thioesters

1. The thiol-containing analogue of puromycin, 6-dimethylamino-9-{1′-[3′-(2″-mercapto-3″-phenylpropionamido)-3′-deoxy-β-d-ribofuranosyl]}purine (XVII) in which the primary amino group of the antibiotic is replaced with a thiol grouping, was synthesized chemically (compound XVII is abbreviated to thi...

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Hlavní autoři: Gooch, John, Hawtrey, Arthur O.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1975
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165607/
https://ncbi.nlm.nih.gov/pubmed/1103886
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