CD4(+) T Cells Which React to the Leishmania major LACK Antigen Rapidly Secrete Interleukin-4 and Are Detrimental to the Host in Resistant B10.D2 Mice

Leishmania major induces the rapid production of interleukin-4 (IL-4) in both susceptible BALB/c and resistant B10.D2 mice. In both strains, IL-4 is produced by T cells which react to the parasite LACK (for Leishmania homolog of the receptor for activated C kinase) antigen. The rapid production of I...

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Vydáno v:	Infect Immun
Hlavní autoři:	Julia, Valérie, Glaichenhaus, Nicolas
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Host Response and Inflammation
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3641-3644.1999
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