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Enhanced In Vivo Immune Responses to Bacterial Lipopolysaccharide by Exogenous CD40 Stimulation

The lack of specific T-cell help in immune responses to thymus-independent antigens results in weak, predominantly immunoglobulin M-mediated immunity with little or no memory. In the work presented here we show how the exogenous stimulation of CD40 by monoclonal antibodies can mimic T-cell help, res...

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Detalles Bibliográficos
Main Authors: Barr, Tom A., Heath, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC116555/
https://ncbi.nlm.nih.gov/pubmed/10377150
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