Pseudomonas aeruginosa Gene Products PilT and PilU Are Required for Cytotoxicity In Vitro and Virulence in a Mouse Model of Acute Pneumonia

Type IV pili of the opportunistic pathogen Pseudomonas aeruginosa mediate twitching motility and act as receptors for bacteriophage infection. They are also important bacterial adhesins, and nonpiliated mutants of P. aeruginosa have been shown to cause less epithelial cell damage in vitro and have d...

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Pubblicato in:	Infect Immun
Autori principali:	Comolli, James C., Hauser, Alan R., Waite, Leslie, Whitchurch, Cynthia B., Mattick, John S., Engel, Joanne N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Molecular and Cellular Pathogenesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.7.3625-3630.1999
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