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The equilibrium position of the reaction of bovine liver glutamate dehydrogenase with pyridoxal5'-phosphate. A demonstration that covalent modification with this reagent completely abolishes catalytic activity.

1. The activity of bovine liver glutamate dehydrogenase incubated with pyridoxal 5'-phosphate declined to a steady value reached within 30--60 min. The residual activity depended on the concentration of modifier up to about 5 mM. Above this concentration, however, no further inactivation was pr...

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Autors principals: Chen, S S, Engel, P C
Format: Artigo
Idioma:Inglês
Publicat: 1975
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165449/
https://ncbi.nlm.nih.gov/pubmed/1237292
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