Identification and Characterization of TspA, a Major CD4(+) T-Cell- and B-Cell-Stimulating Neisseria-Specific Antigen

In search for novel T-cell immunogens involved in protection against invasive meningococcal disease, we screened fractionated proteins of Neisseria meningitidis (strain SD, B:15:P1.16) by using peripheral blood mononuclear cells (PBMCs) and specific T-cell lines obtained from normal individuals and...

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Bibliographic Details
Main Authors: Kizil, Goksel, Todd, Ian, Atta, Mustafa, Borriello, S. Peter, Ait-Tahar, Kamel, Ala’Aldeen, Dlawer A. A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC116541/
https://ncbi.nlm.nih.gov/pubmed/10377136
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