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Effect of buffer composition on binding of adenosine 3':5'-cyclic monophosphate by bovine adrenal extracts.

The binding of cyclic [3H] AMP by bovine adrenal extracts was studied in different buffer systems; 50 mM-Tris/HCl, pH 7.5, buffer containing 4mM-EDTA (disodium salt) offered advantages such as low non-specific interference and high binding affinity. 2-Mercaptoethanol decreased, but EDTA and theophyl...

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Detalhes bibliográficos
Main Authors: Linkola, J, Fyhrquist, F, Weber, T H, Puutula, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1165040/
https://ncbi.nlm.nih.gov/pubmed/202249
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