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Semisynthetic analogues of insulin. The use of N-substituted derivatives of methionine as acid-stable protecting groups
1. We describe the use of benzyloxycarbonylmethionine and ethoxycarbonylmethionine for the selective protection of the amino groups of glycine-A1 and lysine-B29 of pig insulin. We have used the Edman method to remove residues from the N-terminal and of the B-chain of the N(A1)N(B29)-di-protected der...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1977
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1164930/ https://ncbi.nlm.nih.gov/pubmed/921761 |
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