Specificity of interactions of hapten side chains with the combining site of the myeloma protein MOPC 315.

The pKa values of the three histidine residues in the Fv fragment (variable region of the heavy and light chains) of the mouse myeloma protein MOPC 315, measured by high resolution n.m.r. (nuclear magnetic resonance), are 5.9, 6.9 and 8.2. The perturbation of the pKa of one of the histidines (pKa 6....

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Autores principales: Wain-Hobson, S, Dower, S K, Gettins, P, Givol, D, McLaughlin, A C, Pecht, I, Sunderland, C A, Dwek, R A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1977
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164893/
https://ncbi.nlm.nih.gov/pubmed/921746
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