Alloxan cytotoxicity in vitro. Inhibition of rubidium ion pumping in pancreatic beta-cells.

Exposing micro-dissected pancreatic islets of non-inbred ob/ob mice to 2-5 mM-alloxan for 10 min decreased the ability of the islets to accumulate Rb+. Rb+ accumulation in pieces of exocrine pancreas was unaffected by alloxan. When islets were treated with alloxan in the presence of 2-20 mM-D-glucos...

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Bibliografske podrobnosti
Main Authors: Idahl, L A, Lernmark, A, Sehlin, J, Täljedal, I B
Format: Artigo
Jezik:Inglês
Izdano: 1977
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164563/
https://ncbi.nlm.nih.gov/pubmed/192215
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