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Action of human cathepsin G on the oxidized B chain of insulin.

The specificity of cathepsin G, a serine neutral proteinase from human neutrophil leucotyes, was determine dby its action on the insulin B chain. The most susceptible bonds were Phe-24-Phe-25, Leu-15-Tyr-16 and Tyr-16-Leu-17. Other bonds hydrolysed were Leu-6-Cys(O3H)-7, Leu-11-Val-12, Leu-17-Val-18...

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Detalles Bibliográficos
Main Authors: Blow, A M, Barrett, A J
Formato: Artigo
Idioma:Inglês
Publicado: 1977
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164468/
https://ncbi.nlm.nih.gov/pubmed/851418
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