Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

BACKGROUND: The FHIT gene is lost early in the development of many tumors. Fhit possesses intrinsic ApppA hydrolase activity though ApppA cleavage is not required for tumor suppression. Because a mutant form of Fhit that is functional in tumor suppression and defective in catalysis binds ApppA well,...

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Detalhes bibliográficos

Publicado no:	BMC Mol Biol
Principais autores:	Rubio-Texeira, Marta, Varnum, James M, Bieganowski, Pawel, Brenner, Charles
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2002
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12028594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2199-3-7
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