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Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines

BACKGROUND: We describe an alternative method to determine mRNA half-life (t(1/2)) based on the Real-Time RT-PCR procedure. This approach was evaluated by using the β-actin gene as a reference molecule for measuring of mRNA stability. RESULTS: Human leukemia Nalm-6 and CCRF-CEM cells were treated wi...

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Hlavní autoři: Leclerc, Guy J, Leclerc, Gilles M, Barredo, Julio C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC116431/
https://ncbi.nlm.nih.gov/pubmed/11988110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-2-1
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