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Is the 135S Poliovirus Particle an Intermediate during Cell Entry?

Poliovirus binding to its receptor (PVR) on the cell surface induces a conformational transition which generates an altered particle with a sedimentation value of 135S versus the 160S of the native virion. A number of lines of evidence suggest that the 135S particle is a cell entry intermediate. How...

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Autores principales: Huang, Yan, Hogle, James M., Chow, Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC116389/
https://ncbi.nlm.nih.gov/pubmed/10954579
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