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Inhibition by botulinum toxin of depolarization-evoked release of (14C)acetylcholine from synaptosomes in vitro.

1. Cerebral-cortex synaptosomes were shown to synthesize (14C)acetylcholine after incubation with (14C)choline, and 25mM-KCl released (14C)acetylcholine (but not (14C)choline) into the medium by a Ca2+-dependent and Mg2+-sensitive process. 2. The K+-stimulated release of (14C)acetylcholine was inhib...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wonnacott, S, Marchbanks, R M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1976
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163806/
https://ncbi.nlm.nih.gov/pubmed/949350
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