Potential Dengue Virus-Triggered Apoptotic Pathway in Human Neuroblastoma Cells: Arachidonic Acid, Superoxide Anion, and NF-κB Are Sequentially Involved

Direct in vivo evidence for the susceptibility of human neuronal cells to dengue virus has not been reported. In this study, we demonstrated that type 2 dengue (DEN-2) virus infection induced extensive apoptosis in the human neuroblastoma cell line SK-N-SH. Phospholipase A(2) (PLA(2)) was activated...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Jan, Jia-Tsrong, Chen, Bor-Horng, Ma, Shiou-Hwa, Liu, Chiu-I, Tsai, Hui-Ping, Wu, Han-Chung, Jiang, Shian-Yuan, Yang, Kuen-Der, Shaio, Men-Fang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116379/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954569/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.18.8680-8691.2000
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