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Active sites of beta-lactamases. The chromosomal beta-lactamases of Pseudomonas aeruginosa and Escherichia coli.

An acyl-enzyme was isolated from certain chromosomal beta-lactamases and a penicillin. The penicillin was cloxacillin which, although it is a substrate for these enzymes, has such a low kcat. that it functions as an inhibitor. The enzymes were from the mutant of Pseudomonas aeruginosa 18 S that prod...

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Main Authors: Knott-Hunziker, V, Petursson, S, Jayatilake, G S, Waley, S G, Jaurin, B, Grundström, T
格式: Artigo
語言:Inglês
出版: 1982
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163689/
https://ncbi.nlm.nih.gov/pubmed/6807285
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