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Functional modifications of α(2)-macroglobulin by primary amines. Kinetics of inactivation of α(2)-macroglobulin by methylamine, and formation of anomalous complexes with trypsin

The unique steric inhibition of endopeptidases by human α(2)M (α(2)-macroglobulin) and the inactivation of the latter by methylamine were examined in relation to each other. Progressive binding of trypsin by α(2)M was closely correlated with the loss of the methylamine-reactive sites in α(2)M: for e...

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Hlavní autoři: Van Leuven, Fred, Cassiman, Jean-Jacques, Van Den Berghe, Herman
Médium: Artigo
Jazyk:Inglês
Vydáno: 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163616/
https://ncbi.nlm.nih.gov/pubmed/6177314
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