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Functional modifications of α(2)-macroglobulin by primary amines. Kinetics of inactivation of α(2)-macroglobulin by methylamine, and formation of anomalous complexes with trypsin
The unique steric inhibition of endopeptidases by human α(2)M (α(2)-macroglobulin) and the inactivation of the latter by methylamine were examined in relation to each other. Progressive binding of trypsin by α(2)M was closely correlated with the loss of the methylamine-reactive sites in α(2)M: for e...
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| Main Authors: | , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
1982
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1163616/ https://ncbi.nlm.nih.gov/pubmed/6177314 |
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