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Unoccupied binding sites for oestrogen in nuclei of a breast tumour cell line (MCF-7).

1. A method to measure both occupied and unoccupied oestrogen receptors directly in the crude nuclear fraction of the MCF-7 cells was developed. The receptors had high affinity for oestradiol (Kd approx. 0.7 nM) and binding specificity characteristics of oestrogen receptors. 2. A substantial amount...

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Bibliografische gegevens
Hoofdauteurs: Geier, A, Haimsohn, M, Malik, Z, Lunenfeld, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1981
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163572/
https://ncbi.nlm.nih.gov/pubmed/7342967
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