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Binding of nitrobenzylthioinosine to high-affinity sites on the nucleoside-transport mechanism of HeLa cells.

Nitrobenzylthioinosine (NBMPR) binds reversibly, but with high affinity (Kd 0.1--1.2 nM), to inhibitory sites on nucleoside-transport elements of the plasma membrane in a variety of animal cells. The present study explored relationships in HeLa cells between NBMPR binding and inhibition of uridine t...

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Bibliografische gegevens
Hoofdauteurs: Dahlig-Harley, E, Eilam, Y, Paterson, A R, Cass, C E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1981
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163535/
https://ncbi.nlm.nih.gov/pubmed/6280683
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