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Importance of experimental conditions in evaluating the malonyl-CoA sensitivity of liver carnitine acyltransferase. Studies with fed and starved rats.

The experiments reconfirm the powerful inhibitory effect of malonyl-CoA on carnitine acyltransferase I and fatty acid oxidation in rat liver mitochondria (Ki 1.5 microM). Sensitivity decreased with starvation (Ki after 18 h starvation 3.0 microM, and after 42 h 5.0 microM). Observations by Cook, Ott...

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Hlavní autoři: McGarry, J D, Foster, D W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163527/
https://ncbi.nlm.nih.gov/pubmed/7340831
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