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NAD+, ADP-ribosylation and transcription in permeabilized mammalian cells.

When permeabilized hamster fibroblasts were incubated with 4 mM-NAD+, the substrate for poly(ADP-ribose) polymerase, RNA polymerase I activity was inhibited by about 85%. This inhibition was not relieved by prior incubation of cells with 3-aminobenzamide, a potent inhibitor of the poly(ADP-ribose) p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walker, J, Pearson, C K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163440/
https://ncbi.nlm.nih.gov/pubmed/6280677
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