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Development of Minimal Lentivirus Vectors Derived from Simian Immunodeficiency Virus (SIVmac251) and Their Use for Gene Transfer into Human Dendritic Cells

Lentivirus-derived vectors are very promising gene delivery systems since they are able to transduce nonproliferating differentiated cells, while murine leukemia virus-based vectors can only transduce cycling cells. Here we report the construction and characterization of highly efficient minimal vec...

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Published in:J Virol
Main Authors: Mangeot, Philippe-Emmanuel, Nègre, Didier, Dubois, Bertrand, Winter, Arend J., Leissner, Philippe, Mehtali, Majid, Kaiserlian, Dominique, Cosset, François-Loïc, Darlix, Jean-Luc
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2000
Subjects:
Gene Therapy
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC116340/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954529/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.18.8307-8315.2000
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