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Alpha 1-Adrenergic stimulation of Ca2+ mobilization without phosphorylase activation in hepatocytes from phosphorylase b kinase-deficient gsd/gsd rats.

Phenylephrine, vasopressin and the bivalent cation ionophore A23187 mobilized Ca2+ normally, but failed to activate phosphorylase, in hepatocytes from gsd/gsd rats with a deficiency of liver phosphorylase b kinase. These data provide strong evidence that phosphorylase b kinase is the site of action...

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Detalles Bibliográficos
Main Authors: Blackmore, P F, Exton, J H
Formato: Artigo
Idioma:Inglês
Publicado: 1981
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1163259/
https://ncbi.nlm.nih.gov/pubmed/6948557
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