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Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase and of acyl-CoA–cholesterol acyltransferase by the transfer of non-esterified cholesterol to rat liver microsomal vesicles

The incubation of rat liver microsomal fraction with a serum preparation followed by the re-isolation of the microsomal membranes has resulted in an increase in the concentration of non-esterified cholesterol, a considerable decrease in the activity of 3-hydroxy-3-methylglutaryl-CoA reductase and in...

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Detalhes bibliográficos
Main Authors: Mitropoulos, Konstantinos A., Venkatesan, Soundararajan, Reeves, Bernard E. A., Balasubramaniam, Santhirasegaram
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1162740/
https://ncbi.nlm.nih.gov/pubmed/7305980
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