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Drug-induced conversion of liver haem into modified porphyrins. Evidence for two classes of products.
A porphyrin with inhibitory activity towards protohaem ferro-lyase (EC 4.99.1.1) was isolated from the liver of mice given either griseofulvin or isogriseofulvin. This porphyrin resembles closely in chromatographic and spectral properties the inhibitory pigment isolated after treatment with 3,5-diet...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1162524/ https://ncbi.nlm.nih.gov/pubmed/7406869 |
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