Antibody combining sites can be mimicked synthetically. Surface-simulation synthesis of the phosphorylcholine-combining site of myeloma protein M-603.

Antzeko izenburuak

• Binding with lysozyme of antibodies against surface-simulation peptides representing the lysozyme antigenic sites.
  nork: Atassi, M Z, et al.
  Argitaratua: (1982)
• Distance calculation of residues neighbouring to lysozyme antigenic sites. Site-neighbouring residues whose evolutionary substitution can modify the characteristics and binding energy of the sites.
  nork: Atassi, M Z, et al.
  Argitaratua: (1980)
• Delineation of the third antigenic site of lysozyme by application of a novel 'surface-simulation' synthetic approach directly linking the conformationally adjacent residues forming the site.
  nork: Lee, C L, et al.
  Argitaratua: (1976)
• Design of peptide enzymes (pepzymes): surface-simulation synthetic peptides that mimic the chymotrypsin and trypsin active sites exhibit the activity and specificity of the respective enzyme.
  nork: Atassi, M Z, et al.
  Argitaratua: (1993)
• Nearest-neighbour analysis of myoglobin antigenic sites. Nearest-neighbour residues whose replacement can alter the environment of binding-site residue(s) and thus change their characteristics and binding capability.
  nork: Kazim, A L, et al.
  Argitaratua: (1980)